Battletoads & Double Dragon: The Ultimate Team

'After she was defeated by the Battletoads, the evil Dark Queen flees to the outer reaches of the universe and the 'Toads and their mentor get on with their lives. However, one day the Earth's military is neutralized and the giant spaceship Colossus emerges from the Moon. Apparently, the Dark Queen is back with another plan to dominate the galaxy, and she has allied herself with the Shadow Warriors (from the Double Dragon series) to supplement her forces. Deciding to even the odds, the Battletoads contact Billy and Jimmy Lee for help. The brothers agree, and all five immediately take off for the Colossus in a mission to stop this two-pronged threat.'